Mainly there are five factors that affecting the biological risk of the microorganisms
- nature of the microorganisms
- number of the microorganisms
- nature the route of the infection.
- Susceptibility of the microorganisms to treatments
- Susceptibility of the host
Nature of the microorganisms
base on the hazardous level there are 4 categories
BSL – Bio Safety Level
BSL 1 – Unlikely cause human diseases. Minimum potential hazard and laboratory personal, e.g. – Skin diseases, Yeast infection
BSL 2 – Can cause human diseases. Moderate potential hazard to personnel and environment, e.g. – herpes, common cold virus, salmonella
BSL 3 – Can cause severe human diseases, Indigenous or exotic, can cause serious or potential lenthal diseases mainly via inhalation. e.g. – Tubercualsis, SARS – CoV – 2
BSL 4 – Can cause deadly human diseases, Exotics agents, high risk of aerosol-transmitted and life threatening, no vaccines or treatments.
Number of the microorganism
The greater the density of the microorganisms, greater the possibility of the infection of the microorganisms. When density of the microorganisms increases the intensity of the quorum sensing also increases.
Nature the route of the infection
There are many ways to microorganisms to enter the body such as inhalation, ingestion, animals bites, through breaks skin, infections through contaminated sharps.
Susceptibility of the microorganisms to treatments
When more microorganisms strains are appearing, it will increase resistance to antibiotics. Microorganisms having capsules and can form biofilms are more resistant to treatments.
Susceptibility of the host
People having weak immunity(AIDS, Chemotherapy, Organ transplants, stresses), there is a greater risk for serious infection. young and old people are more susceptible to microbial infections than the adults.
